The Clinical Significance of Anti-Bga-51Chromium Survival Studies

نویسندگان

  • P. M. Azar
  • S. Ogawa
  • T. Yasuda
  • S. Yahara
  • H. Saji
  • T. Hosoi
  • H. Fujii
چکیده

An attempt to determine the clinical significance of anti-Bga was performed by transfusing 51Crlabelled red blood cells (RBC) from HLA-B7 positive donors to four patients who had histories of anti-Bga. Pre-and post-transfusion samples showed no change in antibody titer scores, haptoglobin or complement levels. Three of the patients were then transfused with 51Cr-labelled RBC from HLA-B7 negative donors and the half-life (T50Cr) of both were compared. Although low, the T50Cr of HLA-B7 incompatible RBC appeared to be similar to the T50Cr of HLA-B7 compatible RBC.

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تاریخ انتشار 2010